Methyl Methanesulfonate → HCID 86649733, compound

HRID 1484498Notes

Reaction equation

HRID 1484498 reaction equation
[NH2:1][C:2]1[N:3]=[N:4][CH:5]=[CH:6][N:7]=1.[CH3:8][S:9]([O:12]C)(=[O:11])=[O:10].[CH3:14]N(C)C=O>CO>[S:9]([OH:12])(=[O:11])(=[O:10])[CH3:8].[NH2:1][C:2]1[N:3]([CH3:14])[NH:4][CH:5]=[CH:6][N:7]=1

Participants

5

Reactant 3

HCID 4156Methyl MethanesulfonateHCID 6228DimethylformamideHCID 707153-Amino-1,2,4-triazine

Product 1

HCID 86649733HCID 86649733, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of the 3-amino-1,2,4-triazine [6] (500 mg), methyl methanesulphonate (0.5 cm3), dimethylformamide (0.5 cm3) and methanol (10 cm3) was stirred at 60° for 30 mins. and the resulting deep yellow solution allowed to stand at room temperature for 24 hrs. The deep yellow plates that were deposited were filtered off washed with acetone-ether (1:1) and dried.

Workup

  1. waitto stand at room temperature for 24 hrs
  2. filtrationThe deep yellow plates that were deposited were filtered off
  3. washwashed with acetone-ether (1:1)
  4. customdried

Sources & evidence

ORD record
ord-172d09a5b14641fa882f06ec799a51c1
Source dataset
uspto-grants-2016_08
Patent number
US09422253B2

Reaction notes

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