Sulfuryl chloride → HCID 75201754, compound

HRID 1485034Notes

Reaction equation

HRID 1485034 reaction equation
[CH2:1]([C:8]1[C:12]([C:13]2[CH:14]=[C:15](SC)[C:16]3[N:17]([C:19]([CH3:22])=[N:20][N:21]=3)[N:18]=2)=[CH:11][N:10]([CH3:25])[N:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:29])(=O)=O>C(Cl)(Cl)Cl>[CH2:1]([C:8]1[C:12]([C:13]2[CH:14]=[C:15]([Cl:29])[C:16]3[N:17]([C:19]([CH3:22])=[N:20][N:21]=3)[N:18]=2)=[CH:11][N:10]([CH3:25])[N:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 24648Sulfuryl chlorideHCID 75201755HCID 75201755, compound

Product 1

HCID 75201754HCID 75201754, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Conditions

Temperature
25 °C

Procedure

3-benzyl-1-methyl-4-[3-methyl-8-(methylsulfanyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-1H-pyrazole (32 mg; 0.09 mmol) was dissolved in 1 ml chloroform and was treated with sulfurylchlorid (44 μl; 0.54 mmol). The reaction mixture is stirred for 18 h at 25° C.

Sources & evidence

ORD record
ord-7882f9145087457d8cfea0f37687255a
Source dataset
uspto-grants-2016_08
Patent number
US09422290B2

Reaction notes

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