HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydro-4H-pyran-4-one → Methyl DL-2-(1-Boc-piperidin-4-yl)-beta-glycinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydro-4H-pyran-4-one | HCID 121599 | — |
| Reactant | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| Reactant | Methyl 4-aminotetrahydro-2H-pyran-4-acetate | HCID 25418820 | — |
| Product | Methyl DL-2-(1-Boc-piperidin-4-yl)-beta-glycinate | HCID 25418816 | — |
Reaction Steps
Instead of tetrahydro-4H-pyran-4-one, 1-(tert-butoxycarbonyl)-4-piperidone (5.00 g) was used and treated by the same techniques as in Reference Example 1-1(1) and (2) to give the titled compound as a colorless solid (4.65 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09422240B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-ea8d12b67da74676ad9d6522619276da |
| Source note | uspto-grants-2016_08 |