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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1485043Generated: October 31, 2026

(3R)-3-Amino-4-hydroxybutanoic acid → HCID 131736733, compound

https://huagongshe.com/reaction/1485043

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3R)-3-Amino-4-hydroxybutanoic acidHCID 1502076—
Reactant1,4-Dioxane hydrochlorideHCID 20443148—
SolventMethanolHCID 887—
ProductHCID 131736733HCID 131736733—

Reaction Conditions

Temperature60 °C

Reaction Steps

To a solution of L-β-homoserine (1.00 g) in methanol (8.4 mL), a 4 mol/L hydrogen chloride-1,4-dioxane solution (8.4 mL) was added and thereafter the mixture was stirred at 60° C. for 3 hours. The reaction mixture was concentrated under reduced pressure to give the titled compound as a pale yellow oil (1.42 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09422240B2
Source datasetuspto-grants-2016_08
ORD IDord-f5fb4ea35bae423f8338fe1aadb4b25c
Source noteuspto-grants-2016_08