Methanesulfinyl chloride → HCID 118863919, compound

HRID 1485632Notes

Reaction equation

HRID 1485632 reaction equation
[NH2:1][C:2]1[CH:3]=[N:4][C:5]([Cl:8])=[N:6][CH:7]=1.[CH3:9][S:10](Cl)=[O:11]>>[Cl:8][C:5]1[N:6]=[CH:7][C:2]([NH:1][S:10]([CH3:9])=[O:11])=[CH:3][N:4]=1

Participants

3

Reactant 2

HCID 548463Methanesulfinyl chlorideHCID 122159932-Chloropyrimidin-5-amine

Product 1

HCID 118863919HCID 118863919, compound

Procedure

The title compound is prepared from 5-amino-2-chloropyrimidine and methanesulfinyl chloride following a procedure analogous to that described for Intermediate 3 (Step 1). The reaction mixture is cooled in an ice bath for the entire reaction time. LC (method 1): tR=0.49 min; Mass spectrum (ESI+): m/z=192 [M+H]+.

Workup

  1. temperatureThe reaction mixture is cooled in an ice bath for the entire reaction time

Sources & evidence

ORD record
ord-dd69d225ad7c4c8486c5f97251f2cc94
Source dataset
uspto-grants-2016_08
Patent number
US09422312B2

Reaction notes

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