反应详情

温度

75 °C

Into a 2 L round-bottom flask was placed hexadecyl bromide (250 g), 2-methoxypropanol (250 mL), and triethylamine (200 mL). The flask was heated without stirring at 75° C. for 96 h and the contents were concentrated on a Rotavap at 75° C. and 20 mbar. To the residue, methyl tert-butyl ether (800 mL) was added. The slurry was vigorously stirred by a mechanical stirrer for 12 h, filtered, washed with 3 portions (400 mL each) of methyl tert-butyl ether, and dried in vacuum to obtain the product as a white solid in nearly quantitative yield.

1. customInto a 2 L round-bottom flask was placed
2. temperatureThe flask was heated
3. concentrationthe contents were concentrated on a Rotavap at 75° C.
4. additionTo the residue, methyl tert-butyl ether (800 mL) was added
5. stirringThe slurry was vigorously stirred by a mechanical stirrer for 12 h
6. filtrationfiltered
7. washwashed with 3 portions (400 mL each) of methyl tert-butyl ether
8. customdried in vacuum