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HRID1486427

反应详情

EQUATION

反应方程式

HRID 1486427 的结构方程式

REACTANTS

反应物

4
结构：O
HCID962

Water

H2O

结构：O=S(=O)(O)O
HCID1118

Sulfuric acid

H2O4S

结构：S=C=Nc1c2ccccc2nc2ccccc12
HCID82090

9-Isothiocyanatoacridine

C14H8N2S

结构：CNC(C)[C@@H]1CC[C@@H](N)[C@@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3OC[C@](C)(O)[C@H](NC)[C@H]3O)[C@H](N)C[C@@H]2N)O1.CN[C@@H]1[C@@H](O)[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@H](C(C)N)CC[C@H]3N)[C@@H](N)C[C@H]2N)OC[C@]1(C)O.CN[C@@H]1[C@@H](O)[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@H](CN)CC[C@H]3N)[C@@H](N)C[C@H]2N)OC[C@]1(C)O.O=S(=O)(O)O
HCID9855350

未命名化合物

PRODUCTS

生成物

1
结构：Nc1cccc2nc3ccccc3cc12
HCID11352

1-Acridinamine

C13H10N2

收率 910.6%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

4 次

PROCEDURE

实验过程

9-Isothiocyanatoacridin (100 mg) was dissolved in MeOH (5 mL), and added to the solution of gentamicin sulfate (250 mg) in 5 mL MeOH and some drops of water, followed by the solution of BaO (100 mg) in 5 mL MeOH. The suspension was stirred 30 min, neutralized with 3% H2SO4 in MeOH, filtered, evaporated to dryness and the residue was washed carefully with dichloromethane. Obtained 297 mg of yellow powder.

WORKUP

后处理

  1. filtrationfiltered
  2. customevaporated to dryness
  3. washthe residue was washed carefully with dichloromethane