Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 1-Acridinamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | 9-Isothiocyanatoacridine | HCID 82090 | — |
| 반응물 | Gentamicin Sulfate | HCID 9855350 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 1-Acridinamine | HCID 11352 | 910.6% |
반응 단계
9-Isothiocyanatoacridin (100 mg) was dissolved in MeOH (5 mL), and added to the solution of gentamicin sulfate (250 mg) in 5 mL MeOH and some drops of water, followed by the solution of BaO (100 mg) in 5 mL MeOH. The suspension was stirred 30 min, neutralized with 3% H2SO4 in MeOH, filtered, evaporated to dryness and the residue was washed carefully with dichloromethane. Obtained 297 mg of yellow powder.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09427406B2 |
| 출처 데이터셋 | uspto-grants-2016_08 |
| ORD ID | ord-5a66c58179864bdf88f5c0b726aeec75 |
| 출처 메모 | uspto-grants-2016_08 |