1,4-Dioxane hydrochloride → HCID 117920437, compound

HRID 1486606Notes

Reaction equation

HRID 1486606 reaction equation
[ClH:1].O1CCOCC1.[C:8]([N:19]1[CH2:24][CH2:23][CH:22]([N:25]([CH3:27])[CH3:26])[CH2:21][CH2:20]1)(=[O:18])/[CH:9]=[CH:10]/[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17]>C(Cl)Cl>[ClH:1].[C:8]([N:19]1[CH2:20][CH2:21][CH:22]([N:25]([CH3:27])[CH3:26])[CH2:23][CH2:24]1)(=[O:18])/[CH:9]=[CH:10]/[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17]

Participants

4

Reactant 2

HCID 204431481,4-Dioxane hydrochlorideHCID 89881791HCID 89881791, compound

Product 1

HCID 117920437HCID 117920437, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

In addition, an oily product Compound 12 was dissolved in methylene chloride, and treated with hydrogen chloride-dioxane, to produce 1-((E)-2-decenoyl)-4-dimethylaminopiperidine hydrochloride (crystals, mp 185°-188° C.).

Sources & evidence

ORD record
ord-48c6f4eb640d43b2adfda5dd5a0228b4
Source dataset
uspto-grants-2016_08
Patent number
US09428477B2

Reaction notes

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