1,4-Dioxane hydrochloride → HCID 117920672, compound

HRID 1486616Notes

Reaction equation

HRID 1486616 reaction equation
[ClH:1].O1CCOCC1.[C:8]([N:19]1[CH2:24][CH2:23][N:22]([CH2:25][CH2:26][C:27]([OH:29])=[O:28])[CH2:21][CH2:20]1)(=[O:18])/[CH:9]=[CH:10]/[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17]>C(Cl)Cl>[ClH:1].[C:8]([N:19]1[CH2:24][CH2:23][N:22]([CH2:25][CH2:26][C:27]([OH:29])=[O:28])[CH2:21][CH2:20]1)(=[O:18])/[CH:9]=[CH:10]/[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17]

Participants

4

Reactant 2

HCID 204431481,4-Dioxane hydrochlorideHCID 89881737HCID 89881737, compound

Product 1

HCID 117920672HCID 117920672, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

In addition, the low-melting point crystals Compound 21 were dissolved in methylene chloride, and treated with hydrogen chloride-dioxane, to produce 3-[4((E)-2-decenoyl)piperazin-1-yl]propionic acid hydrochloride (crystals, mp 201°-203° C.).

Sources & evidence

ORD record
ord-878b18de57e14e658572d37972099d7d
Source dataset
uspto-grants-2016_08
Patent number
US09428477B2

Reaction notes

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