HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Bromomethyl)-5-methyl-1,3-dioxol-2-one → HCID 72550764, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Bromomethyl)-5-methyl-1,3-dioxol-2-one | HCID 10774141 | — |
| Reactant | (1S,2S,3S,5R,6S)-3'-((allyloxy)carbonyl)-3-fluoro-5'-oxospiro[bicyclo[3.1.0]hexan-2,4'-oxazolidine]-6-carboxylic acid | HCID 117987522 | — |
| Product | HCID 72550764 | HCID 72550764 | 27% |
Reaction Steps
(1S,2S,3S,5R,6S)-3′-((Allyloxy)carbonyl)-3-fluoro-5′-oxospiro[bicyclo[3.1.0]hexan-2,4′-oxazolidine]-6-carboxylic acid (A-1-2, 660 mg) and 4-(bromomethyl)-5-methyl-1,3-dioxol-2-one (639 mg) were treated in the same manner as in Example A-1 (3) and (4) to give the title compound (A-16, 188 mg) as a pale yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09428483B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-5832ca116eea48898d6bdac2976fd5eb |
| Source note | uspto-grants-2016_08 |