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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1486680Generated: October 31, 2026

4-(Bromomethyl)-5-methyl-1,3-dioxol-2-one → HCID 72550764, compound

https://huagongshe.com/reaction/1486680

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Bromomethyl)-5-methyl-1,3-dioxol-2-oneHCID 10774141—
Reactant(1S,2S,3S,5R,6S)-3'-((allyloxy)carbonyl)-3-fluoro-5'-oxospiro[bicyclo[3.1.0]hexan-2,4'-oxazolidine]-6-carboxylic acidHCID 117987522—
ProductHCID 72550764HCID 7255076427%

Reaction Steps

(1S,2S,3S,5R,6S)-3′-((Allyloxy)carbonyl)-3-fluoro-5′-oxospiro[bicyclo[3.1.0]hexan-2,4′-oxazolidine]-6-carboxylic acid (A-1-2, 660 mg) and 4-(bromomethyl)-5-methyl-1,3-dioxol-2-one (639 mg) were treated in the same manner as in Example A-1 (3) and (4) to give the title compound (A-16, 188 mg) as a pale yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09428483B2
Source datasetuspto-grants-2016_08
ORD IDord-5832ca116eea48898d6bdac2976fd5eb
Source noteuspto-grants-2016_08