Benzaldehyde, 2-methoxy-5-nitro- → 1-(5-Amino-2-methoxy-benzyl)-piperidine-4-carboxylic acid tert-butylamide

Beteiligte Stoffe

Reaktionsschritte

The title compound is prepared according to the reactions described for BB-5 above starting from 2-methoxy-5-nitro-benzaldehyde and piperidine-4-carboxylic acid tert-butylamide yielding after reductive amination 1-(2-methoxy-5-nitro-benzyl)-piperidine-4-carboxylic acid tert-butylamide; LC-MS A: tR=0.61 min; [M+H]+=350.18 followed by reduction with stannous chloride the title compound; LC-MS A: tR=0.42 min; [M+H]+=320.24.

Herkunft & Nachweise