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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1486745Generated: October 30, 2026

Hydrochloric Acid → 5-Fluoro-pyridine-2-carboxylic acid (3-formyl-phenyl)-amide

https://huagongshe.com/reaction/1486745

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant5-Fluoro-pyridine-2-carboxylic acid (3-[1,3]dioxolan-2-yl-phenyl)-amideHCID 131736815—
Product5-Fluoro-pyridine-2-carboxylic acid (3-formyl-phenyl)-amideHCID 113892326—

Reaction Steps

The title compound is prepared by treatment with HCl 10% of 5-fluoro-pyridine-2-carboxylic acid (3-[1,3]dioxolan-2-yl-phenyl)-amide: LC-MS A: tR=0.79 min; [M+H]+=245.05.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09428456B2
Source datasetuspto-grants-2016_08
ORD IDord-0bc0f52ab6734b1c92eca57ec738a94d
Source noteuspto-grants-2016_08