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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1486855Generated: October 31, 2026

Trifluoroacetic acid → HCID 178512539, compound

https://huagongshe.com/reaction/1486855

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 178450901HCID 178450901—
ProductHCID 178512539HCID 178512539—

Reaction Steps

A mixture of tert-butyl (5S)-5-(2-tert-butoxy-2-oxoethyl)-3-(3-((4-carbamimidamidobenzoyl)oxy)phenyl)-4,5-dihydro-1,2-oxazole-5-carboxylate (3.29 g) and TFA (30 mL) was stirred at room temperature for 2 hours. The reaction mixture was concentrated under reduced pressure, and then, the residue was washed with diethyl ether to obtain the title compound (3.01 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09428470B2
Source datasetuspto-grants-2016_08
ORD IDord-89bf9360f9974b8f8f729376d3a0f42c
Source noteuspto-grants-2016_08