HuagongsheHuagongshe Chemistry Print Report · For research reference only
Urea → HCID 178470753, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Urea | HCID 1176 | — |
| Reactant | Triethyl ethane-1,1,2-tricarboxylate | HCID 81961 | — |
| Reactant | 2,4-dichloro-7-(4-methoxybenzyl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine | HCID 86699670 | — |
| Product | HCID 178470753 | HCID 178470753 | 52.4% |
Reaction Steps
According to General Protocol I, 2,4-dichloro-7-(4-methoxybenzyl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine was prepared from triethyl ethane-1,1,2-tricarboxylate (10 g, 41 mmol) and urea (2.44 g, 41 mmol), and isolated as a pale-yellow solid (4.6 g, yield 35%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09428508B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-871773f941e34ba48642bb99c940ecc2 |
| Source note | uspto-grants-2016_08 |