Isopropylamine → HCID 90161040, compound

Participants

Reaction Conditions

Reaction Steps

6-bromo-8-chloro-3-methyl-[1,2,4]triazolo[4,3-a]pyrazine J-1 (30.00 g; 121.2 mmol), isopropylamine (14.30 g; 242.44 mmol) and hünigbase (17.20 g; 133.33 mmol) are dissolved in 150 ml NMP and are stirred for 2 hours at 80° C. The reaction mixture is diluted with water and extracted with EtOAc. The organic layer is separated and dried over MgSO4 and evaporated to dryness.

Provenance & Evidence