Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1487897Generated: October 30, 2026

Tert-butyl 4-(4-cyanophenyl)piperidine-1-carboxylate → Tert-butyl 4-([1,2,4]triazolo[4,3-a]pyridin-7-yl)piperidine-1-carboxylate

https://huagongshe.com/reaction/1487897

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl 4-(4-cyanophenyl)piperidine-1-carboxylateHCID 22492960—
Reactant7-Bromo-[1,2,4]triazolo[4,3-a]pyridineHCID 23115966—
ProductTert-butyl 4-([1,2,4]triazolo[4,3-a]pyridin-7-yl)piperidine-1-carboxylateHCID 90066679—

Reaction Steps

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 1.1, except 7-bromo-[1,2,4]triazolo[4,3-a]pyridine (compound 41.2) was used in place of 4-bromobenzonitrile. m/z (ES+) 303 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09428502B2
Source datasetuspto-grants-2016_08
ORD IDord-408153a5fa5f40138da2fc241cad9777
Source noteuspto-grants-2016_08