HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Piperidin-4-yl)benzonitrile--hydrogen chloride (1/1) → 3-Chloro-7-(piperidin-4-yl)imidazo[1,5-a]pyridine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Piperidin-4-yl)benzonitrile--hydrogen chloride (1/1) | HCID 19391618 | — |
| Reactant | Tert-butyl 4-(4-cyanophenyl)piperidine-1-carboxylate | HCID 22492960 | — |
| Reactant | Tert-butyl 4-(3-chloroimidazo[1,5-a]pyridin-7-yl)piperidine-1-carboxylate | HCID 90029531 | — |
| Product | 3-Chloro-7-(piperidin-4-yl)imidazo[1,5-a]pyridine hydrochloride | HCID 118250879 | — |
Reaction Steps
The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 1.2, except tert-butyl 4-(3-chloroimidazo[1,5-a]pyridin-7-yl)piperidine-1-carboxylate (compound 68.2) was used in place of tert-butyl 4-(4-cyanophenyl)piperidine-1-carboxylate (compound 1.1) to yield the title compound as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09428502B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-09947d91a2a241f48084a96503534fd4 |
| Source note | uspto-grants-2016_08 |