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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1487973Generated: October 30, 2026

Methyl 4-cyclopropyl-2-methyl-5-(5-methyl-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-2-yl)benzoate → Methyl 4-cyclobutyl-2-methyl-5-(5-methyl-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-2-yl)benzoate

https://huagongshe.com/reaction/1487973

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-cyclopropyl-2-methyl-5-(5-methyl-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-2-yl)benzoateHCID 90020876—
ReactantMethyl 4-cyclopropyl-5-formyl-2-methylbenzoateHCID 90021238—
ReactantMethyl 4-cyclobutyl-5-formyl-2-methylbenzoateHCID 90021669—
ProductMethyl 4-cyclobutyl-2-methyl-5-(5-methyl-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-2-yl)benzoateHCID 90021589—

Reaction Steps

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 87.4, except methyl 4-cyclobutyl-5-formyl-2-methylbenzoate (compound 82.5) was used in place of methyl 4-cyclopropyl-5-formyl-2-methylbenzoate (compound 87.1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09428502B2
Source datasetuspto-grants-2016_08
ORD IDord-e4263633a74c4e03834c0638e0275cfa
Source noteuspto-grants-2016_08