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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1487991Generated: November 2, 2026

Methyl 4-bromo-2-methylbenzoate → Methyl 4-fluoro-5-iodo-2-methylbenzoate

https://huagongshe.com/reaction/1487991

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-bromo-2-methylbenzoateHCID 22031226—
Reactant4-Fluoro-5-iodo-2-methylbenzoic acidHCID 90021560—
ProductMethyl 4-fluoro-5-iodo-2-methylbenzoateHCID 90021566—

Reaction Steps

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 6.1, except 4-fluoro-5-iodo-2-methylbenzoic acid (compound 101.1) was used in place of 4-bromo-2-methylbenzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09428502B2
Source datasetuspto-grants-2016_08
ORD IDord-35a1c6b3b0604e92a31176c016fdbb19
Source noteuspto-grants-2016_08