Pyrrolidine → 6-(Pyrrolidin-1-YL)pyridine-3,4-diamine

HRID 1488003Notes

Reaction equation

HRID 1488003 reaction equation
[N:1]1([C:7]2[CH:12]=[C:11]([NH2:13])[C:10]([N+:14]([O-])=O)=[CH:9][N:8]=2)[CH2:6][CH2:5]O[CH2:3][CH2:2]1.N1CCCC1>>[N:1]1([C:7]2[N:8]=[CH:9][C:10]([NH2:14])=[C:11]([NH2:13])[CH:12]=2)[CH2:6][CH2:5][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 31268PyrrolidineHCID 900216182-(Morpholin-4-yl)-5-nitropyridin-4-amine

Product 1

HCID 682882956-(Pyrrolidin-1-YL)pyridine-3,4-diamine

Procedure

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 151.1 and 151.2, except pyrrolidine was used in place of morpholine.

Sources & evidence

ORD record
ord-2fb64cc2060445a4ace0f83840de8698
Source dataset
uspto-grants-2016_08
Patent number
US09428502B2

Reaction notes

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