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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1488023Generated: October 30, 2026

4-(Piperidin-4-yl)benzonitrile--hydrogen chloride (1/1) → HCID 178425799, compound

https://huagongshe.com/reaction/1488023

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Piperidin-4-yl)benzonitrile--hydrogen chloride (1/1)HCID 19391618—
Reactant4-(Azetidin-3-yl)benzonitrile hydrochlorideHCID 55254991—
Reactant2,4-Dimethyl-5-(4-methyl-2-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl)benzoic acidHCID 90029976—
ReactantHCID 178425884HCID 178425884—
ProductHCID 178425799HCID 178425799—

Reaction Steps

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 164, except 4-methyl-3-(4-methyl-2-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl)benzoic acid (compound 168.1) was used in place of 2,4-dimethyl-5-(4-methyl-2-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl)benzoic acid (compound 164.2) and 4-(piperidin-4-yl)benzonitrile hydrochloride (compound 1.2) was used in place of 4-(azetidin-3-yl)benzonitrile hydrochloride (compound 5.2) m/z (ES+) 469 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09428502B2
Source datasetuspto-grants-2016_08
ORD IDord-a4627dcd1cb546e6aac7941c44ff7880
Source noteuspto-grants-2016_08