P-Toluic Acid → Methyl 3-(2-bromopropanoyl)-4-methylbenzoate

HRID 1488075Notes

Reaction equation

HRID 1488075 reaction equation
[Br:1][CH:2]([CH3:17])[C:3]([C:5]1[C:6]([CH3:16])=[CH:7][C:8](C)=[C:9]([CH:14]=1)[C:10]([O:12][CH3:13])=[O:11])=[O:4].CC1C=CC(C(O)=O)=CC=1>>[Br:1][CH:2]([CH3:17])[C:3]([C:5]1[CH:14]=[C:9]([CH:8]=[CH:7][C:6]=1[CH3:16])[C:10]([O:12][CH3:13])=[O:11])=[O:4]

Participants

3

Reactant 2

HCID 7470P-Toluic AcidHCID 90021223Methyl 5-(2-bromopropanoyl)-2,4-dimethylbenzoate

Product 1

HCID 90021391Methyl 3-(2-bromopropanoyl)-4-methylbenzoate

Procedure

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 1.6, except 4-methylbenzoic acid was used in place of 2,4-dimethylbenzoic acid.

Sources & evidence

ORD record
ord-10bf255181cf4164a2d9e57939c34037
Source dataset
uspto-grants-2016_08
Patent number
US09428502B2

Reaction notes

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