Hydrazine hydrate (1:1) → HCID 90029563, compound
Reaction equation
[CH3:1][CH:2]([C:5](=O)[CH:6]1[CH2:10][CH2:9][O:8][CH2:7]1)[CH:3]=O.O.[NH2:13][NH2:14]>C(O)C>[CH3:1][C:2]1[CH:3]=[N:13][NH:14][C:5]=1[CH:6]1[CH2:10][CH2:9][O:8][CH2:7]1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 80 °C
Procedure
Into a 100-mL round-bottom flask, was placed a solution of 2-methyl-3-oxo-3-(tetrahydrofuran-3-yl)propanal (compound 263.3, 3.00 g, 19.2 mmol) in ethanol (25 mL). Hydrazine hydrate (1.16 mL, 24 mmol) was added and the resulting solution was stirred for 3 h at 80° C. The resulting mixture was concentrated under reduced pressure to obtain the title compound as a colorless oil (3.5 g, crude).
Workup
- customInto a 100-mL round-bottom flask, was placed
- concentrationThe resulting mixture was concentrated under reduced pressure
Sources & evidence
- ORD record
- ord-550f9aca6b634bdca46f268ea30b6693
- Source dataset
- uspto-grants-2016_08
- Patent number
- US09428502B2
Reaction notes
Loading…