HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → p-(Benzyloxy)phenethyl alcohol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Tyrosol | HCID 10393 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Solvent | Acetone | HCID 180 | — |
| Solvent | Water | HCID 962 | — |
| Product | p-(Benzyloxy)phenethyl alcohol | HCID 3017260 | — |
Reaction Steps
A mixture of 4-hydroxyphenethyl alcohol (15.02 g), benzyl bromide (13.6 ml), and potassium carbonate (75.1 g) in acetone (250 ml) is heated at reflux for about 4 hours. The mixture is cooled and poured into ether and water. The organic layer is washed with water, 1N sodium hydroxide solution, brine, dried over magnesium sulfate, filtered and concentrated in vacuo to give 4-benzyloxyphenethyl alcohol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05674482 |
| Source dataset | uspto-grants-1997_10 |
| ORD ID | ord-b2691b85c0e342e2a1caeac5db949915 |
| Source note | uspto-grants-1997_10 |