HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1488341Generated: October 26, 2026
Tributyl phosphite → Dibutyl 4-benzyloxybenzylphosphonate
https://huagongshe.com/reaction/1488341
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tributyl phosphite | HCID 7623 | — |
| Reactant | 4-Benzyloxybenzyl chloride | HCID 70042 | — |
| Product | Dibutyl 4-benzyloxybenzylphosphonate | HCID 22904634 | — |
Reaction Steps
A mixture of 4-benzyloxybenzyl chloride (4.99 g) and tri-n-butylphosphite is heated at 50° C. for about 4 hours while removing butyl chloride. The mixture is cooled to room temperature and the crude product purified by HPLC on silica, eluting with 25% ethyl acetate in hexane, to give dibutyl 4-benzyloxybenzylphosphonate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05674482 |
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| Source dataset | uspto-grants-1997_10 |
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| ORD ID | ord-b7147a46d7644a8d9099f48843f6d485 |
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| Source note | uspto-grants-1997_10 |
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