Benzyl Alcohol → Benzyl-2-(S)-N-boc-amino-2-biphenyl propionate

HRID 148837Notes

Reaction equation

HRID 148837 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]([C:10](=[O:11])[OH:12])[CH2:13][c:14]1[cH:15][cH:16][c:17](-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:18][cH:19]1.[CH2:34]([Cl:35])[Cl:36].[CH3:37][N:38]([CH3:39])[c:40]1[cH:41][cH:42][n:43][cH:44][cH:45]1.[OH:26][CH2:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]([C:10]([O:11][CH2:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)=[O:12])[CH2:13][c:14]1[cH:15][cH:16][c:17](-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:18][cH:19]1

Participants

5

Reactant 4

HCID 244Benzyl AlcoholHCID 6344DichloromethaneHCID 142844-(Dimethylamino)pyridineHCID 46239082-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoic Acid

Product 1

HCID 14523715Benzyl-2-(S)-N-boc-amino-2-biphenyl propionate

Sources & evidence

ORD record
ord-f49036ebc5dd47f091640f090aa160e3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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