HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-Methyl-2-propenyl)-4-acetamido-3-bromo-2,6-dimethylanisole → N-Acetyl-5-methoxy-3,3,4,6-tetramethylindoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-Methyl-2-propenyl)-4-acetamido-3-bromo-2,6-dimethylanisole | HCID 22905663 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | N-Acetyl-5-methoxy-3,3,4,6-tetramethylindoline | HCID 22905632 | 85% |
Reaction Steps
Treatment of 14 (1.9 g, 5.8 mmoI) according to the general procedure used for Pd-catalyzed cyclization afforded 15 (1.2 g, 85% yield) as a viscous liquid. 13C NMR: δ 11.6, 16.4, 24.1, 26.9, 41.1, 59.9, 64.7, 116.7, 126.5, 129.7, 135.7, 137.8, 153.4, 168.0; HRMS: calcd. for C15H21NO2 247.1572, fnd. 247.1581.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05674876 |
| Source dataset | uspto-grants-1997_10 |
| ORD ID | ord-678c60dd8fa64714976652c632c6f9a7 |
| Source note | uspto-grants-1997_10 |