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HRID1488463

反应详情

EQUATION

反应方程式

HRID 1488463 的结构方程式

REACTANTS

反应物

1
结构：C=C(C)CN(C(C)=O)c1cc(C)c(OC)c(C)c1Br
HCID22905663

未命名化合物

PRODUCTS

生成物

1
结构：COc1c(C)cc2c(c1C)C(C)(C)CN2C(C)=O
HCID22905632

未命名化合物

收率 85%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：[Pd]
催化剂HCID23938

Palladium

Pd

PROCEDURE

实验过程

Treatment of 14 (1.9 g, 5.8 mmoI) according to the general procedure used for Pd-catalyzed cyclization afforded 15 (1.2 g, 85% yield) as a viscous liquid. 13C NMR: δ 11.6, 16.4, 24.1, 26.9, 41.1, 59.9, 64.7, 116.7, 126.5, 129.7, 135.7, 137.8, 153.4, 168.0; HRMS: calcd. for C15H21NO2 247.1572, fnd. 247.1581.