Cesium carbonate → HCID 88301792, compound

HRID 1488873Notes

Reaction equation

HRID 1488873 reaction equation
C(=O)([O-])[O-].[Cs+:5].[Cs+].[C:7]1([C:13]([C:39]2[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=2)([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][C:30]([OH:32])=[O:31])[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>O1CCCC1>[Cs+:5].[C:7]1([C:13]([C:39]2[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=2)([C:33]2[CH:34]=[CH:35][CH:36]=[CH:37][CH:38]=2)[O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][C:30]([O-:32])=[O:31])[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1

Participants

4

Reactant 2

HCID 10796Cesium carbonateHCID 54403154HCID 54403154, compound

Product 1

HCID 88301792HCID 88301792, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Aqueous cesium carbonate (1M, 0.16 ml) was added dropwise to a solution of 16-triphenylmethoxyhexadecanoic acid (0.16 g, 0.31 mmol) from Example 1b(i) above in tetrahydrofuran (10 ml) until the pH reached approximately 8, whereupon the solvent was removed under reduced pressure and the residue dried under vacuum for 2 hours. The oily semicrystalline residue was dispersed in dry dimethylformamide (10 ml) and evaporated to dryness in vacuo.

Workup

  1. customwhereupon the solvent was removed under reduced pressure
  2. customthe residue dried under vacuum for 2 hours
  3. additionThe oily semicrystalline residue was dispersed in dry dimethylformamide (10 ml)
  4. customevaporated to dryness in vacuo

Sources & evidence

ORD record
ord-b1686d03b8fd45ebaccafa1837dd2eeb
Source dataset
uspto-grants-1997_10
Patent number
US05676925

Reaction notes

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