Hydrogen Bromide → HCID 178421369, compound

HRID 1488938Notes

Reaction equation

[NH2:1][C:2]1[NH:3][CH:4]=[C:5]([C:7]2[C@:8]3([CH2:25][CH2:24][C@H:23]4[C@@H:13]([CH2:14][CH:15]=[C:16]5[C@:21]4([CH3:22])[CH2:20][CH2:19][C@H:18]([OH:26])[CH2:17]5)[C@@H:10]3[CH2:11][CH:12]=2)[CH3:9])[N:6]=1.Br>>[NH2:1][C:2]1[NH:3][CH:4]=[C:5]([C:7]2[C@:8]3([CH2:25][CH2:24][C@H:23]4[C@@H:13]([CH2:14][CH:15]=[C:16]5[C@:21]4([CH3:22])[CH2:20][CH2:19][C:18](=[O:26])[CH2:17]5)[C@@H:10]3[CH2:11][CH:12]=2)[CH3:9])[N:6]=1

Participants

Reactant 2

HCID 260Hydrogen Bromide

HCID 178421248HCID 178421248, compound

Product 1

HCID 178421369HCID 178421369, compound

Procedure

In an analogous manner to example 2 the title compound is prepared from (3β)-17-(2-amino-4-imidazolyl)-androsta-5,16-dien-3-ol.HBr prepared in Example 7.

Sources & evidence

ORD record: ord-b016b18cf02e49c2bef487150ff81256
Source dataset: uspto-grants-1997_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05677293

Reaction notes

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