Hydrochloric Acid → HCID 86753092, compound

Participants

Reaction Steps

The procedure is carried out as in Example 1 but starting with 1 g of 1-(6-chloro-1-oxo-2-indanyl)imidazole-2-carboxamide, a total of 75 ml of methanol and 15 ml of 12N aqueous hydrochloric acid solution. 0.4 g of 7-chloro-5H, 10H-imidazo [1,2-a]indeno[1,2-e]pyrazin-4-one hydrochloride is obtained which decomposes without melting above 300° C. [NMR spectrum: (300 MHz; DMSO-d6 ; δ in ppm): 4.12 (s, 2H: --CH2-- in position 10); 7.44 (dd, J=8 and 1 Hz 1H: --H8); 7.66 (d, J=8 Hz, 1H: --H9); 7.95 and 8.25 (2s broad, 1H each: --H of imidazole); 8.05 (d, j=1 Hz, 1H: --H6); 12.97 (unresolved complex, 1H: --CONH--)].

Provenance & Evidence