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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1489082Generated: October 29, 2026

2-Chloro-1,3-oxazole → HCID 22099715, compound

https://huagongshe.com/reaction/1489082

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-1,3-oxazoleHCID 13371074—
ReactantHCID 22100000HCID 22100000—
SolventDimethylformamideHCID 6228—
SolventDichloromethaneHCID 6344—
ProductHCID 22099715HCID 22099715—

Reaction Steps

To a suspension of 6-(2-methylbenzoylamino)nicotinic acid (0.3 g) in dimethylformamide (0.5 ml) and dichloromethane (2.5 ml) is added dropwise oxazolyl chloride (0.2 ml), and the mixture is stirred at room temperature for 2 hours. The mixture is evaporated under reduced pressure to remove the solvent to give 6-(2-methylbenzoylamino)nicotinoyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05677299
Source datasetuspto-grants-1997_10
ORD IDord-3f726e84d5534d528eb64149da3cdc36
Source noteuspto-grants-1997_10