HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4,5,6,7-Tetrahydro-1H-benzo(d)imidazole-5-carboxylic acid hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethyl 4,5,6,7-tetrahydro-1H-benzo[d]imidazole-6-carboxylate | HCID 21222281 | — |
| Product | 4,5,6,7-Tetrahydro-1H-benzo(d)imidazole-5-carboxylic acid hydrochloride | HCID 53231038 | — |
Reaction Steps
A 0.3 g portion of this ethyl (+)-4.5,6,7-tetrahydrobenzimidazole-5-carboxylate was dissolved in 2 ml of 6N hydrochloric acid and refluxed for 1.5 hours, and then evaporated to dryness under reduced pressure to obtain 4,5,6,7-tetrahydrobenzimidazole-5-carboxylic acid hydrochloride with the optical rotation indicated below. mp: 245°-248° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05677326 |
| Source dataset | uspto-grants-1997_10 |
| ORD ID | ord-03ee7c386b1c427d83ca0571a43337fd |
| Source note | uspto-grants-1997_10 |