N-Methylbenzylamine → HCID 22903695, compound

HRID 1489163Notes

Reaction equation

[CH2:1]([N:8]1[C:12](=[O:13])[CH2:11][C:10]([C:19]([O-:21])=O)([C:14]([O:16][CH2:17][CH3:18])=[O:15])[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:22]([NH:29][CH3:30])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[CH2:1]([N:8]1[C:12](=[O:13])[CH2:11][C:10]([C:19](=[O:21])[N:29]([CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH3:30])([C:14]([O:16][CH2:17][CH3:18])=[O:15])[CH2:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 7669N-Methylbenzylamine

HCID 86751384HCID 86751384, compound

Product 1

HCID 22903695HCID 22903695, compoundYield 78.7%

Procedure

Monoethyl 1-benzyl-5-oxopyrrolidine-3,3-dicarboxylate (29.1 g) obtained in Preparative Example 1 (1) and N-benzyl-N-methylamine (12.1 g) were treated in the same manner as in Preparative Example 1 (2) to give 31 g of the object compound as an oil.

Sources & evidence

ORD record: ord-6f80d433ec4443bca37c0b04a0c35529
Source dataset: uspto-grants-1997_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05677316

Reaction notes

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