Sodium Iodide → HCID 10037716, compound

HRID 1489189Notes

Reaction equation

HRID 1489189 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9]Br)=[CH:4][CH:3]=1.[I-:11].[Na+]>CC(C)=O>[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][I:11])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 5238Sodium IodideHCID 5731534-Fluorophenethyl bromide

Product 1

HCID 10037716HCID 10037716, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture containing 2-(4-fluorophenyl)ethyl bromide (see Preparation 76) (10 g), sodium iodide (10 g) and acetone (200 ml) was stirred at room temperature for 20 hours then filtered. The filtrate was concentrated in vacuo to give the title compound as a colourless oil, 12 g.

Workup

  1. filtrationthen filtered
  2. concentrationThe filtrate was concentrated in vacuo

Sources & evidence

ORD record
ord-c129db27fd984b40a7860e40eec4924e
Source dataset
uspto-grants-1997_10
Patent number
US05677324

Reaction notes

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