Hydrochloric Acid → HCID 19350728, compound

Participants

Reaction Steps

0.8 g of 1-acetylamino-2,3-dihydro-3,4-dimethyl-2-oxo-1H-imidazole are suspended in 800 ml of methanol, and the suspension is then heated to 42°. At this temperature, 28 g of gaseous HCl are passed into the suspension in the course of 40 minutes, during which process the suspension turns into a solution and the temperature of the reaction mixture rises to 52°. The solution is concentrated on a rotary evaporator, the residue is stirred with a small amount of tetrahydrofuran, and the crystals which have precipitated are filtered off with suction and dried, yielding the title salt melting at 162°-165°.

Provenance & Evidence