4-[5-(4-Fluorophenoxy)-2-furanyl]-2-thiazolamine → HCID 54719500, compound

Participants

Reaction Steps

0.339 g (0.99 mmol) of methyl 6-(2-furanyl)-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxylate 1,1-dioxide and 0.398 g (1.44 mmol) of 4-[5-(4-fluorophenoxy)-2-furanyl]-2-thiazolamine are heated to boiling in 3 ml of absolute xylene. After 4.5 h, the suspension is cooled, and the precipitated product is filtered off, digested several times with diethyl ether and recrystallized from dimethyl sulphoxide/acetone 10:1.

Provenance & Evidence