Sodium Hydroxide → HCID 23669088, compound

Participants

Reaction Steps

2-[N,N-bis-(2-hydroxyethyl)amino]-2-methylpropanoic acid (423.46 grams, 2.21 moles) (this material is about 99% pure; it contains 1% H2O) is added with stirring to a cooled solution of pure sodium hydroxide (88.57 grams, 2.21 moles) in pyrogen-free distilled water (400 ml.). The mixture is stirred until solution is effected. After reaching room temperature, the solution is stirred while enough pyrogen-free distilled water is added to make the total volume 1,000 ml. The solution is sterilized by filtration. This solution contains 47.4% by weight of, or is 2.21 molar in, sodium 2-[N,N-bis-(2-hydroxyethyl)-amino]-2-methylpropanoate.

Provenance & Evidence