2,4,6-Trimethylbenzaldehyde → HCID 86749382, compound

HRID 1489922Notes

Reaction equation

HRID 1489922 reaction equation
[C:1]1([PH:7](=[O:14])[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:15][C:16]1[CH:23]=[C:22]([CH3:24])[CH:21]=[C:20]([CH3:25])[C:17]=1[CH:18]=[O:19].C[O-].[Na+]>C1(C)C=CC=CC=1>[OH:19][CH:18]([P:7](=[O:14])([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)[C:17]1[C:16]([CH3:15])=[CH:23][C:22]([CH3:24])=[CH:21][C:20]=1[CH3:25]

Participants

5

Reactant 3

HCID 102542,4,6-TrimethylbenzaldehydeHCID 254003Diphenylphosphine oxideHCID 10942334Sodium Methoxide

Product 1

HCID 86749382HCID 86749382, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

To 101 g (0.5 mol) of diphenyl phosphine oxide and 74 g (0.5 mol) of 2,4,6-trimethylbenzaldehyde in 150 mL of toluene there were added 0.5 g of a 30 wt % strength sodium methylate solution. The product began to crystallize after 10 minutes and was isolated in the usual manner. Yield: 98%.

Workup

  1. customto crystallize after 10 minutes
  2. customwas isolated in the usual manner

Sources & evidence

ORD record
ord-164c2dcd289a41adad9c139e59ce239d
Source dataset
uspto-grants-1997_10
Patent number
US05679863

Reaction notes

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