Thionyl Chloride → HCID 86751451, compound

Participants

Reaction Steps

0.9 ml (12 mmol) of thionyl chloride are added dropwise, at 0° C., to 4.1 g (10 mmol) of (1-(2-tertbutoxycarbonylaminoethyl)-3-(methoxycarbonylphenylmethyl)ureido)acetic acid in 50 ml of methanol. The mixture is allowed to warm to room temperature and then stirred further overnight, followed by filtering off with suction and drying.

Provenance & Evidence