Ethyl Acetate → HCID 54562442, compound

HRID 1490337Notes

Reaction equation

HRID 1490337 reaction equation
C(OCC)(=O)C.[N+:7]([C:10]1[CH:15]=[C:14]([O:16][CH3:17])[C:13]([O:18][CH3:19])=[CH:12][C:11]=1[CH:20]1[CH2:25][CH2:24][O:23][C:21]1=[O:22])([O-])=O.[H][H]>[Pt]=O.C(O)C>[CH3:19][O:18][C:13]1[CH:12]=[C:11]2[C:10](=[CH:15][C:14]=1[O:16][CH3:17])[NH:7][C:21](=[O:22])[CH:20]2[CH2:25][CH2:24][OH:23]

Participants

6

Reactant 3

HCID 8857Ethyl AcetateHCID 21480995HCID 21480995, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 54562442HCID 54562442, compoundYield 99.1%

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 702EthanolSolvent

Procedure

An ethyl acetate solution containing 2.0 g of α-(2-nitro-4,5-dimethoxyphenyl)-butyrolactone and 500 mg of platinum oxide was stirred in a 2.0 atm. hydrogen gas atmosphere. Ethanol was added to the reaction mixture, followed by filtration. The solvent was evaporated to yield 1.76 g of the title compound.

Workup

  1. filtrationfollowed by filtration
  2. customThe solvent was evaporated

Sources & evidence

ORD record
ord-18261618640f40d3aa9daa39e9859b95
Source dataset
uspto-grants-1997_10
Patent number
US05681954

Reaction notes

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