HCID 21481038, compound → HCID 54167170, compound

Participants

Reaction Steps

In 50 ml of methanol was dissolved 1.50 g of 1-benzyloxycarbonyl-4-(3-(2-ethoxycarbonylethyl)carbonylamino-2-methylphenyl)piperazine, and 1.0 g of 10% palladium-on-carbon was added thereto, followed by stirring at room temperature in a hydrogen atmosphere for 2 hours. The reaction mixture was filtered and the solvent was evaporated to yield 0.99 g of 3-(2-ethoxycarbonylethyl)carbonylamino-2-methylphenylpiperazine, which was used in the next reaction without purification.

Provenance & Evidence