HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490495Generated: October 31, 2026
HCID 2774264, compound → HCID 70975102, compound
https://huagongshe.com/reaction/1490495
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 2774264 | HCID 2774264 | — |
| Reagent | Pinacol | HCID 6425 | — |
| Reagent | Triethylamine | HCID 8471 | — |
| Reagent | Catecholborane | HCID 67506 | — |
| Catalyst | Tris(pentafluorophenyl)borane | HCID 582056 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 70975102 | HCID 70975102 | 42% |
Reaction Steps
Prepared from 2-fluoro-N,N-dimethylaniline (1g, 27.8 mg, 0.200 mmol, 1.00 equiv) and catBH (36.0 mg, 0.300 mmol, 1.50 equiv) according to GP 1. The title compound was purified by flash column chromatography using cyclohexane/EtOAc/Et3N (30/1/1) as eluent to afford 3g (22.2 mg, 42%) as a white solid.
Provenance & Evidence
| DOI | 10.1002/anie.201611536 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-c97bc2351f1641abbf2646050cc1f606 |
|---|
| Source note | Borylation dataset from Roche |
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