HCID 178444789, compound → N,N-dihexyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethoxy)benzamide

HRID 1490841Notes

Reaction equation

HRID 1490841 reaction equation
CCCCCCN(CCCCCC)C(=O)c1ccccc1OC(F)(F)F>C1=CCCC=CCC1.C1=CCCC=CCC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].Cc1ccc(C)cc1.O=C(Nc1ccccc1-c1ccc(-c2ccccn2)nc1)NC1CCCCC1.[Ir].[Ir]>CCCCCCN(CCCCCC)C(=O)c1cc(B2OC(C)(C)C(C)(C)O2)ccc1OC(F)(F)F.CCCCCCN(CCCCCC)C(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1OC(F)(F)F

Participants

7

Reactant 1

HCID 178444789HCID 178444789, compound

Product 2

HCID 91820771N,N-dihexyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethoxy)benzamideYield 87%HCID 140762156N,N-dihexyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethoxy)benzamideYield 12%

Reagents, catalysts & solvents 4

HCID 2733548Bis(pinacolato)diboraneReagentHCID 91820779HCID 91820779, compoundReagentHCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridiumCatalystHCID 7809P-XyleneSolvent

Conditions

Temperature
25 °C

Sources & evidence

ORD record
ord-7b42bf7d806a45c394276e20f5fad2d5
Source dataset
Borylation dataset from Roche

Reaction notes

Loading…