Diethyl (2-bromophenyl)phosphonate → HCID 164681383, compound

HRID 1490892Notes

Reaction equation

HRID 1490892 reaction equation
CCOP(=O)(OCC)c1ccccc1Br>C1=CCCC=CCC1.C1=CCCC=CCC1.CC(C)(C)c1ccnc(-c2cc(C(C)(C)C)ccn2)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].Cc1ccc(C)cc1.[Ir].[Ir]>CCOP(=O)(OCC)c1cc(B2OC(C)(C)C(C)(C)O2)ccc1Br.CCOP(=O)(OCC)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1Br

Participants

7

Reactant 1

HCID 284858Diethyl (2-bromophenyl)phosphonate

Product 2

HCID 91820751HCID 91820751, compoundYield 24%HCID 164681383HCID 164681383, compoundYield 75%

Reagents, catalysts & solvents 4

HCID 2733548Bis(pinacolato)diboraneReagentHCID 42491874,4'-Di-tert-butyl-2,2'-bipyridylReagentHCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridiumCatalystHCID 7809P-XyleneSolvent

Conditions

Temperature
40 °C

Sources & evidence

ORD record
ord-d3c399f67a70416196da1a285db6001c
Source dataset
Borylation dataset from Roche

Reaction notes

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