1-Hexylpiperidine → 1-[6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)hexyl]piperidine

HRID 1490990Notes

Reaction equation

HRID 1490990 reaction equation
CCCCCCN1CCCCC1>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCCCCCC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].Cc1ccc2ccc3cccnc3c2n1.[Ir].[Ir]>CC1(C)OB(CCCCCCN2CCCCC2)OC1(C)C

Participants

6

Reactant 1

HCID 5232531-Hexylpiperidine

Product 1

HCID 1624148851-[6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)hexyl]piperidineYield 63%

Reagents, catalysts & solvents 4

HCID 2733548Bis(pinacolato)diboraneReagentHCID 49133562-Methyl-1,10-phenanthrolineReagentHCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridiumCatalystHCID 9266CyclooctaneSolvent

Conditions

Temperature
100 °C

Sources & evidence

ORD record
ord-04774ceac0e04925b547f57d94f715cc
Source dataset
Borylation dataset from Roche

Reaction notes

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