HCID 44782514, compound → HCID 178431118, compound

HRID 1491118Notes

Reaction equation

HRID 1491118 reaction equation
CC(C(=O)Nc1ccc(F)cc1F)N1C(=O)c2ccccc2C1=O>CC#N.CC(=O)O.CC(=O)O.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CC[N+](CC)(CC)CC.COc1cc(OC)c2ccccc2n1.F[B-](F)(F)F.O=C(O)O.[K].[Pd]>CC1(C)OB(CC(C(=O)Nc2ccc(F)cc2F)N2C(=O)c3ccccc3C2=O)OC1(C)C

Participants

9

Reactant 1

HCID 44782514HCID 44782514, compound

Product 1

HCID 178431118HCID 178431118, compoundYield 15%

Reagents, catalysts & solvents 7

HCID 176Acetic AcidReagentHCID 1424362,4-DimethoxyquinolineReagentHCID 2724277Tetraethylammonium tetrafluoroborateReagentHCID 2733548Bis(pinacolato)diboraneReagentHCID 45051578carbonic acid, potassium saltReagentHCID 58759193palladium(I) acetateCatalystHCID 6342AcetonitrileSolvent

Conditions

Temperature
80 °C

Sources & evidence

ORD record
ord-df003b9a0e264f948fe1303b0810a159
Source dataset
Borylation dataset from Roche

Reaction notes

Loading…