HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1491135Erstellt: 25. Oktober 2026
Benzene, 1-methyl-4-(methylthio)- → 4,4,5,5-Tetramethyl-2-(5-methyl-2-(methylthio)phenyl)-1,3,2-dioxaborolane
https://huagongshe.com/reaction/1491135
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Benzene, 1-methyl-4-(methylthio)- | HCID 69334 | — |
| Reagenz | 4,4'-Dimethyl-2,2'-bipyridine | HCID 14338 | — |
| Reagenz | Bis(pinacolato)diborane | HCID 2733548 | — |
| Katalysator | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Lösungsmittel | P-Xylene | HCID 7809 | — |
| Produkt | 4,4,5,5-Tetramethyl-2-(5-methyl-2-(methylthio)phenyl)-1,3,2-dioxaborolane | HCID 138983642 | 41% |
| Produkt | HCID 178503150 | HCID 178503150 | 20% |
Reaktionsschritte
dtbpy: A mixture of ortho- and meta-borylated products (79 mg, 61% yield, ortho/meta + para = 2.0); meta-Isomer 5d was obtained by further purification by GPC (18 mg, 14% yield), yellow solid (mp. 85-87 oC)
Herkunft & Nachweise
| DOI | 10.1002/anie.201610041 |
|---|
| Quelldatensatz | Borylation dataset from Roche |
|---|
| ORD ID | ord-8ab19278bad6421ab2de79245143ed07 |
|---|
| Quellennotiz | Borylation dataset from Roche |
|---|
