HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491140Generated: October 25, 2026
4-Phenylthioanisole → 4,4,5,5-Tetramethyl-2-(2-methylsulfanyl-5-phenylphenyl)-1,3,2-dioxaborolane
https://huagongshe.com/reaction/1491140
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Phenylthioanisole | HCID 11019897 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagent | 2-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine | HCID 134956623 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | P-Xylene | HCID 7809 | — |
| Product | 4,4,5,5-Tetramethyl-2-(2-methylsulfanyl-5-phenylphenyl)-1,3,2-dioxaborolane | HCID 132510262 | 86% |
Reaction Steps
Ligand 3f: A mixture of ortho- and meta-borylated products (140 mg, 86% yield, ortho/meta + para = >30); ortho-borylated product 4g was obtained by further purification by GPC (128 mg, 79% yield), white solid (mp. 116-118 oC)
Provenance & Evidence
| DOI | 10.1002/anie.201610041 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-a2d89378380b4f06b6a03649928343ec |
|---|
| Source note | Borylation dataset from Roche |
|---|
